home

Details
Last Updated on Friday, 11 September 2026 07:25

 

6th Annual Scientific Meeting of the Association for Haemophilia and Allied Disorders–Asia Pacific (AHAD-AP 2026). This meeting will be held in person in Bangkok, Thailand, from 10–13 September 2026, in collaboration with the Thai Society of Haematology.

Details
Last Updated on Wednesday, 09 September 2026 16:06

Reengineering Coagulation with a Bispecific Antibody

 

Flora Peyvandi, M.D., Ph.D.1,2
For decades, the treatment of hemophilia A rested
on a single principle: replacing factor VIII (see Key
Concepts), the missing clotting factor. Plasma-
derived and recombinant factor VIII concentrates
transformed a once-fatal disease into a manage-
able chronic condition through prophylaxis and
treatment. But factor VIII has a relatively short
half-life and thus is administered through fre-
quent intravenous infusions, and neutralizing
anti–factor VIII antibodies (inhibitors) that render
replacement therapy ineffective develop in up to
one third of patients with severe hemophilia A.1-3
By showing that the coagulation cascade could be
activated in the absence of factor VIII, Kunihiro
Hattori, Tomoyuki Igawa, and Takehisa Kitazawa
(of Chugai Pharmaceutical) overcame these limi-
tations. They developed a bispecific antibody that
mimics blood coagulation factor VIII, an achieve-
ment recognized by the 2026 Lasker–DeBakey
Clinical Medical Research Award.

https://www.nejm.org/doi/full/10.1056/NEJMcibr2608873

 

Details
Last Updated on Saturday, 25 July 2026 05:44

 

 

 

Details
Last Updated on Saturday, 25 July 2026 05:44
 
 

 

EAHAD Presidential Interview: Flora Peyvandi

Flora Peyvandi | Professor of Internal Medicine, University of Milan, Italy; European Association for Haemophilia and Allied Disorders (EAHAD) Congress President

Citation: EMJ Hema. 2024;12[1]:xx-xx

Can you share what initially drew you to the field of haematology, and what continues to drive you today?

I love to do medicine, and I always wanted to do internal medicine-haematology, because I thought haematology was just facing up to blood, and blood is everywhere in every organ. That was one of the main reasons. I was very interested in the process of clotting and the complexity of clotting, and then I ended up being interested in the bleeding area, which is part of haematology.

You’ve earned degrees and conducted research at prestigious institutions across Italy, the Netherlands, the UK, and the USA. How have these diverse academic experiences shaped your approach to haematology research and patient care?

read more

 

 

 

Details
Last Updated on Friday, 23 January 2026 08:00

Dalla fisiopatologia alla diagnosi avanzata: modelli convergenti di
ECCELLENZA e INNOVA

 

23 gennaio 2026 ore 14:00 – 17:30
Sala Rappresentanza, Università degli Studi di Milano
Via Festa del Perdono 7 – 20122 Milano

read more

 

Details
Last Updated on Monday, 19 January 2026 17:58

L'Università Statale inaugura l'anno accademico 2025-2026

 

 

read more